Search on: 3-ISOPROPYLMALATE DEHYDROGENASE 
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Descriptor English:   3-Isopropylmalate Dehydrogenase 
Descriptor Spanish:   3-Isopropilmalato Deshidrogenasa 
Descriptor Portuguese:   3-Isopropilmalato Desidrogenase 
Tree Number:   D08.811.682.047.820.193
Definition English:   An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE. 
History Note English:   2006(1980); use DICARBOXYLIC ACIDS 1970-1979 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50598 
Unique Identifier:   D050539 

Occurrence in VHL:
 

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